Hypopituitarism  Following Traumatic  Brain Injury: Neuroendocrine Dysfunction and Head Trauma - Amar Agha - Livros - LAP Lambert Academic Publishing - 9783838304434 - 11 de janeiro de 2010
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Hypopituitarism Following Traumatic Brain Injury: Neuroendocrine Dysfunction and Head Trauma

Amar Agha

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Hypopituitarism Following Traumatic Brain Injury: Neuroendocrine Dysfunction and Head Trauma

Neuroendocrine derangements after traumatic brain injury (TBI) have received increasing recognition in recent years. Marked changes of the hypothalamo-pituitary axis have been documented in the acute phase of TBI with as many as 80% of patients showing evidence of gonadotropin deficiency, 18% of growth hormone deficiency, 16% of corticotrophin deficiency and 40% of patients demonstrating vasopressin abnormalities. Longitudinal prospective studies have shown that some of the early abnormalities are transient, while new endocrine dysfunction becomes apparent in the post acute phase. There remains a high frequency of hypothalamic-pituitary hormone deficiencies among long term survivors of TBI with approximately 28% patients showing one or more pituitary hormone deficiencies. This is a higher frequency than previously thought and suggests that most cases of post traumatic hypopituitarism (PTHP) remain undiagnosed and untreated. The data underscore the need for the identification and appropriate timely management of hormone deficiencies, in order to optimise patient recovery from head trauma.

Mídia Livros     Paperback Book   (Livro de capa flexível e brochura)
Lançado 11 de janeiro de 2010
ISBN13 9783838304434
Editoras LAP Lambert Academic Publishing
Páginas 200
Dimensões 225 × 11 × 150 mm   ·   316 g
Idioma German  

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