Transactions on Computational Systems Biology Xiii

Brief Description: This book covers Computational Models for Cell Processes, featuring enhanced contributions from the CompMod workshop (2009). Covers a wide range of topics in systems biology, addressing the dynamics and the computational principles of this emerging field. Review Quotes: From the reviews: This collection of papers offers a great synopsis of the actual trends in systems biology. In this book, researchers, students, and computational biologists will find examples of various modern time- and space-dependent prediction and simulation methods and models. The wealth of methods and approaches presented in this collection is clear evidence that great progress has been made in modeling many particular aspects of systems biology. (Adrian Pasculescu, ACM Computing Reviews, April, 2012) Jacket Description/Back: The LNCS journal "Transactions on Computational Systems Biology" is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena. This, the 13th "Transactions on Computational Systems Biology" volume, guest edited by Ralph-Johan Back, Ion Petre, and Erik de Vink, focuses on "Computational Models for Cell Processes" and features a number of carefully selected and enhanced contributions initially presented at the CompMod workshop, which took place in Eindhoven, The Netherlands, in November 2009. From different points of view and following various approaches, the papers cover a wide range of topics in systems biology, addressing the dynamics and the computational principles of this emerging field. Review Quotes: From the reviews: This collection of papers offers a great synopsis of the actual trends in systems biology. In this book, researchers, students, and computational biologists will find examples of various modern time- and space-dependent prediction and simulation methods and models. The wealth of methods and approaches presented in this collection is clear evidence that great progress has been made in modeling many particular aspects of systems biology. (Adrian Pasculescu, ACM Computing Reviews, April, 2012)"Marc Notes: The volume is based on the CompMod workshop that took place in Eindhoven, the Netherlands, on November 2, 2009.; Includes bibliographical references and index. Table of Contents: Evolutionary Dynamics of a Population of Cells with a Toxin Suppressor Gene / Antti HAkkinen, Fred G. Biddle, Olli-Pekka Smolander, Olli Yli-Harja, Andre S. Ribeiro -- Translation from the Quantified Implicit Process Flow Abstraction in SBGN-PD Diagrams to Bio-PEPA Illustrated on the Cholesterol Pathway / Laurence Loewe, Maria Luisa Guerriero, Steven Watterson, Stuart Moodie, Peter Ghazal, Jane Hillston -- Impulse-Based Dynamic Simulation of Deformable Biological Structures / Rhys Goldstein, Gabriel Wainer -- Delay Stochastic Simulation of Biological Systems: A Purely Delayed Approach / Roberto Barbuti, Giulio Caravagna, Andrea Maggiolo-Schettini, Paolo Milazzo -- Modelling Ammonium Transporters in Arbuscular Mycorrhiza Symbiosis / Mario Coppo, Ferruccio Damiani, Maurizio Drocco, Elena Grassi, Mike Guether, Angelo Troina -- Genetically Regulated Metabolic Networks: Gale-Nikaido Modules and Differential Inequalities / Ovidiu Radulescu, Anne Siegel, Elisabeth PEcou, ClEment Chatelain, Sandrine Lagarrigue -- Cultural Epigenetics: On the Heritability of Complex Diseases / Rodrick Wallace, Deborah Wallace -- Refining Dynamics of Gene Regulatory Networks in a Stochastic ?-Calculus Framework / LoIc PaulevE, Morgan Magnin, Olivier Roux -- Author Index.

Contributor Bio:  Back, Ralph-Johan Back-Abo Akademi, Finland