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Linkage Disequilibrium and Association Mapping: Analysis and Applications - Methods in Molecular Biology 2007 edition
Andrew R Collins
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Linkage Disequilibrium and Association Mapping: Analysis and Applications - Methods in Molecular Biology 2007 edition
Andrew R Collins
As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In this book, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike.
Marc Notes: Includes bibliographical references and index. Table of Contents: Dedication -- Preface -- Contributors -- 1. Linkage Disequilibrium and Association Mapping: An Introduction / Andrew R. Collins -- 2. A History of Association Mapping / Newton E. Morton -- 3. Linkage Disequilibrium Maps and Location Databases / William Tapper -- 4. LDMAP: The Construction of High-Resolution Linkage Disequilibrium Maps of the Human Genome / Tai-Yue Kuo, Winston Lau, Andrew R. Collins -- 5. Linkage Disequilibrium as a Tool for Detecting Signatures of Natural Selection / Sarah Ennis -- 6. The Genetic Basis of Complex Traits: Rare Variants or Common Gene, Common Disease? / Sudha K. Iyengar, Robert C. Elston -- 7. Linkage Disequilibrium Mapping for Complex Disease Genes / Andrew DeWan, Robert J. Klein, Josephine Hoh -- 8. Linkage Disequilibrium Maps and Disease-Association Mapping / Nikolas Maniatis -- 9. Coalescent Methods for Fine-Scale Disease-Gene MappingAndrew P. Morris -- 10. Family-Based Linkage Disequilibrium Tests Using General Pedigrees / Yin Yao Shugart, Lina Chen, Rui Li, Terri Beaty -- 11. Association Studies Using Familial Cases: An Efficient Strategy for Identifying Low-Penetrance Disease Alleles / Emily L. Webb, Richard S. Houlston -- 12. Association Mapping Using Pooled DNA / Hsin-Chou Yang, Cathy S. J. Fann -- 13. Selecting Single-Nucleotide Polymorphisms for Association Studies With SNPbrowser Software / Francisco M. De La Vega -- 14. Avoiding False Discoveries in Association Studies / Chiara Sabatti -- 15. Gene Mapping in Asthma-Related Traits / Tarja Laitinen -- 16. Identifying Susceptibility Variants for Type 2 Diabetes / Eleftheria Zeggini, Mark I. McCarthy -- Index. Publisher Marketing: 'Linkage Disequilibrium and Association Mapping' discusses the progress that has been made in the gene-mapping process. Review Citations:
Scitech Book News 12/01/2007 pg. 51 (EAN 9781588296696, Hardcover)
| Mídia | Livros Hardcover Book (Livro com lombada e capa dura) |
| Lançado | 23 de agosto de 2007 |
| ISBN13 | 9781588296696 |
| Editoras | Humana Press Inc. |
| Páginas | 255 |
| Dimensões | 152 × 229 × 15 mm · 589 g |
| Idioma | English |
| Editor | Collins, Andrew R. |
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