Cell Cycle Inhibitors in Cancer Therapy: Current Strategies - Cancer Drug Discovery and Development 2003 edition

Marc Notes: Includes bibliographical references and index. Review Quotes: "Cell Cycle Inhibitors in Cancer Therapy is an excellent book that summarizes the most up-to-date information on cell cycle control mechanisms, the naturally occurring and synthetic molecules that modulate cell cycle events, and their potential roles in cancer therapeutics and prevention." -Pharmaceutical ResearchTable of Contents: Cdk Inhibitors: Background and Introduction Giulia De Falco, Catherine Soprano, and Antonio Giordano p27, A Prognostic Indicator Reflecting...? Andrew Koff Cell Cycle Control of Transcription at the G1/S Phase Transition Andre J. van Wijnen, Gary S. Stein, Janet L. Stein, and Jane B. Lian Tumor-Suppressor Genes as Diagnostic Tools Lorenzo Leoncini, Cristiana Bellan, Caterina Cinti, and Antonio Giordano Regulation of Cell Cycle and Apoptosis Lucio Miele CDK Inhibitors as Targets of Chemoprevention Agents Joanna K. Sax and Wafik S. El-Deiry Cell Cycle Regulatory Genes as Targets of Retinoids Kenneth J. Soprano, Sijie Zhang, Dongmei Zhang, William F. Holmes, Valeria Masciullo, Antonio Giordano, and Dianne R. Soprano Modulators of Cyclin-Dependent Kinases: A Novel Therapeutic Approach for the Treatment of Neoplastic Diseases Adrian M. Senderowicz Cell Cycle Regulators: Interactions and Their Role in Diagnosis, Prognosis, and Treatment of Cancer Paul J. van Diest and Rob J. A. M. Michalides Cell Cycle Regulators as Targets of Anticancer Therapy Mikhail V. Blagosklonny Mammalian CDK Inhibitors as Targets of Ubiquitinization in Cancer Valeria Masciullo, Kenneth J. Soprano, and Antonio Giordano Synthetic Oligopeptides as Cancer Cell Cycle Modulators Anna Severino, Armando Felsani, Antonio Giordano, and Marco G. Paggi Index"Publisher Marketing: This text provides information about molecules involved in cell cycle control. It presents information derived from the basic sciences to the medical community, where it will have an impact on diagnosis, prognosis and therapeutics for some of the most prevalent diseases.